The dose of Zofran for hyperemesis gravidarum requiring hospitalization is a maximum of 10 milligrams via intravenous therapy (IV) every 8 hours. More typical pregnancy nausea is managed by a much lower oral dose — 4 to 8 mg every 8 hours.
Is Zofran OK to take while pregnant?
Although not specifically approved by the FDA for the management of nausea and vomiting during pregnancy, ondansetron is now commonly used during pregnancy.
How often can you take Zofran 8 mg while pregnant?
Ondansetron can be given orally or intravenously in doses up to 8 mg three to four times daily.
How much Zofran can you take in 24 hours?
The total dose over 24 hours (given as divided doses) must not exceed adult dose of 32 mg. a The intravenous dose must not exceed 8 mg.
Is Zofran safe at 9 weeks pregnant?
A new study published in the New England Journal of Medicine concluded that the popular drug Zofran (used to treat nausea, vomiting and in some cases, hyperemesis gravidarum, in early pregnancy) poses no risk to the developing fetus.
Will taking Zofran once hurt my baby?
If you are pregnant and have taken ondansetron or Zofran® during pregnancy, I want to reassure you that it likely has not affected your baby. Even if the increased risk for cleft palate or heart defects turns out to be true, the risk to your baby is still very, very small.
Is Zofran linked to birth defects?
Zofran was found to double the risk of heart defects including atrial and ventricular septal (“hole in the heart”) defects and increased the overall risk of birth defects by 30% in one study. Another study found Zofran was linked with a 237% risk of cleft palate defects.
Is too much Zofran bad?
Abnormal Heart Rhythms Zofran can cause QT interval prolongation and a potentially fatal heart rhythm called torsades de pointes. Serotonin Syndrome Larger doses of Zofran or using the medication in combination with other drugs can cause a dangerous rise in serotonin levels.
Can you drink water after taking Zofran?
Place the tablet in the mouth and allow it to dissolve, then swallow. While you may take these tablets with water, it is not necessary to do so.
How quickly does Zofran work?
Zofran (ondansetron) begins to work within about 30 minutes. It reaches peak blood concentrations in about 2 hours. Zofran’s effects can last 8 to 12 hours. The Zofran dosage varies depending on the severity and cause of the nausea and vomiting.
How much Zofran can I take at once?
Adults typically take one 8-mg tablet or rapidly disintegrating tablet or 10 mL of liquid twice a day. For patients ages 12 and older, the dosage is the same as for adults. For those ages 4 to 11, patients should take a 4-mg tablet or rapidly disintegrating tablet or 5 mL of liquid three times per day.
How long does 4mg of Zofran last?
Zofran (ondansetron) lasts about eight hours. It begins to work quickly and reaches peak concentration in about two hours. To prevent nausea, the dose is usually repeated eight hours after the first one. Some people continue this Zofran dosage for 1 to 2 days following chemotherapy or radiation.
Can you still throw up after taking Zofran?
If you vomit within one hour taking your first Zofran Tablet of each course prescribed to you, you should take the same dose again. If you continue to vomit, tell your doctor.
Is it bad to take Zofran every day?
Do not exceed a total daily dose of 8mg in those with severe hepatic impairment. Orally disintegrating Zofran tablets may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).
Does Zofran cause cleft palate?
Women suffering from extreme morning sickness often take Zofran (ondansetron) to combat their debilitating nausea and vomiting. However, two studies have found that the drug may increase risk of heart defects and cleft palate in children exposed in utero.
What nausea medicine is safe for pregnancy?
In fact, the FDA has approved a prescription medication for use during pregnancy that is a combination of Vitamin B6 and Unisom. It is called Diclegis. This is the only FDA approved medication for treating nausea and vomiting during pregnancy.