Are antivirals safe during pregnancy?

Treatment with antiviral medications is recommended for pregnant women or women who are up to 2 weeks postpartum (including following pregnancy loss) with suspected or confirmed influenza and can be taken during any trimester of pregnancy.

Can you take antivirals when pregnant?

Long-term suppressive therapy can significantly reduce these outbreaks and is likely safe during pregnancy. Acyclovir (Zovirax) and valacyclovir (Valtrex) are the drugs most commonly used for herpes outbreak suppression and treatment during pregnancy. These drugs help reduce how active the virus is.

Does acyclovir cause miscarriage?

Does taking acyclovir/valacyclovir increase the chance for miscarriage? Miscarriage can occur in any pregnancy. Studies have not found an increased chance for miscarriage following acyclovir use.

Is acyclovir safe in early pregnancy?

Conclusion: Use of acyclovir in the first trimester does not increase birth defects, and it should be the antiviral drug of choice in early pregnancy.

Does Valtrex cause birth defects?

This large nationwide historical cohort study found no association between exposure to acyclovir, valacyclovir, or famciclovir in the first trimester of pregnancy and the risk of any major birth defect. In analyses of individual antivirals, risk estimates were similar for acyclovir and valacyclovir.

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Can acyclovir harm my baby?

Answer Studies have shown that the use of acyclovir or valacyclovir is not associated with an increase in birth defects. Limited data exist for famciclovir and therefore it would not be considered a first-line choice for treatment of herpes during pregnancy.

What can acyclovir cause while being pregnant?

Acyclovir, an antiviral nucleoside analogue, is a widely used agent highly specific for herpes simplex and varicella-zoster viruses. Unintended exposure to acyclovir early in pregnancy, which is not uncommon, may cause excessive maternal and physician anxiety.

Does acyclovir cross the placenta?

Acyclovir is known to cross the placenta to the fetus. Frenkel et al4 reported the specific pharmacokinetics of acyclovir in pregnant patients with recurrent HSV receiv ing either 200 or 400 mg of acyclovir orally every 8 hours from 38 weeks’ gestation until delivery.

What category is acyclovir for pregnancy?

All formulations of acyclovir are assigned FDA pregnancy category C status ****, which indicates that safety in human pregnancies has not been determined; therefore, the drug should not be used during pregnancy unless the potential benefit justifies the potential risk to the fetus.

What should you not take with acyclovir?

Common medications that may interact with acyclovir include:

  • amphotericin.
  • clozapine.
  • hepatitis B medications, such as entecavir.
  • HIV medications, such as tenofovir and zidovudine.
  • gentamicin.
  • NSAIDs, such as ibuprofen, diclofenac, or naproxen.
  • other antivirals, such as valacyclovir.
  • probenecid.

Can you take acyclovir everyday?

The tablets, capsules, and suspension are usually taken with or without food two to five times a day for 5 to 10 days, starting as soon as possible after your symptoms begin. When acyclovir is used to prevent outbreaks of genital herpes, it is usually taken two to five times a day for up to 12 months.

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Do antivirals weaken immune system?

The inhibitory effects of antivirals on immune cells may contribute to the immune deterioration observed in patients following prolonged use of the drugs.

When should I take Valtrex during pregnancy?

-Recommended regimen for HSV suppressive therapy in pregnant women with recurrent genital herpes: 500 mg orally 2 times a day starting at 36 weeks gestation.

Can I take Valtrex for cold sores while pregnant?

Cold sores are often treated with aciclovir cream which is a specific antiviral medication. This is applied to the affected area. It is considered safe at all stages of pregnancy. If the cold sores are severe, aciclovir or valaciclovir tablets may be prescribed by your GP.

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