Metronidazole is an FDA Pregnancy Category B drug, meaning that animal studies have not revealed evidence of harm to the fetus but that adequate, well-controlled studies among pregnant women have not been conducted.
Is metronidazole safe for pregnancy?
Conclusion: During pregnancy, treating bacterial vaginosis and trichomoniasis with metronidazole is effective and offers no teratogen risk. Benefit of metronidazole in the reduction of preterm birth was demonstrated for the combination of this medication with other antibiotics.
Is metronidazole safe in second trimester?
Use of metronidazole, a common treatment for bacterial vaginosis and Trichomonas vaginalis, should be avoided during the second trimester of pregnancy in this population.
Can metronidazole affect early pregnancy?
In a nested case control study of more than 95,000 pregnant women in Quebec, Canada, researchers from the Universite de Montreal found that the use macrolides (excluding erythromycin), quinolones, tetracyclines, sulfonamides, and metronidazole was associated with increased risk of miscarriage in early pregnancy, with …
Why is metronidazole contraindicated in pregnancy?
Metronidazole is used to treat genitourinary infections and is one of the most commonly used drugs in pregnancy, but it is widely thought to be relatively contraindicated in the first trimester because of a possible increased risk for birth defects.
What can a pregnant woman use to stop purging?
Eat foods that are easy to digest and don’t irritate or stimulate the stomach and digestive tract. The BRAT diet (Bananas, Rice, Applesauce, Toast) plus the nutrients in other easy-to-digest foods (potatoes, chicken and vegetable soup, lean meats) can help until diarrhea has passed.
How do you know if you have BV while pregnant?
Symptoms of BV include:
- Thin vaginal discharge.
- Discharge that is gray, white, or green.
- Foul-smelling or “fishy” vagina odor.
- Vaginal itching.
- Pain in the vagina.
- Burning during urination.
- Burning feeling inside the vagina.
What are the side effects of metronidazole?
Common side effects may include:
- nausea, vomiting, loss of appetite, stomach pain;
- diarrhea, constipation;
- unpleasant metallic taste;
- rash, itching;
- vaginal itching or discharge;
- mouth sores; or.
- swollen, red, or “hairy” tongue.
Can you breastfeed while taking metronidazole?
Daily 2 g oral doses, normally given for 3 days, are considered to be compatible with breastfeeding. Intravenous administration produces similar maternal plasma and milk levels to equivalent oral doses, although the data are limited. Short-course IV metronidazole is considered to be compatible with breastfeeding.
Is BV common in pregnancy?
The Centers for Disease Control and Prevention (also called CDC) estimates that 1 million pregnant women get BV each year. Pregnant women are at increased risk for BV because of hormone changes that happen during pregnancy. Hormones are chemicals made by the body.
How long does metronidazole stay in your system?
The elimination half life of metronidazole is approximately 8 hours. It takes 5.5 x elimination half life for a medicine to be completely cleared from the body. Therefore it will take about 44 hours (5.5 x 8 hrs) for it to be cleared from your system.
Is metronidazole a strong antibiotic?
Flagyl, known generically as metronidazole or by the brand name Protostat, is an antibacterial drug that is classified as a broad-spectrum antibiotic. 1 Metronidazole is used to treat anaerobic bacterial infections or protozoal infections.
What STD is treated with metronidazole?
What is the treatment for trichomoniasis? Trichomoniasis can be cured with a single dose of prescription antibiotic medication (either metronidazole or tinidazole), pills which can be taken by mouth.